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interstitial cystitis
Interstitial cystitis (IC),〔 〕 also known as bladder pain syndrome (BPS), is a chronic inflammatory condition of the submucosal and muscular layers of the bladder. The cause of IC/BPS is currently unknown and the condition is regarded as a diagnosis of exclusion. IC/BPS may be associated with urinary urgency, urinary frequency, waking at night to urinate (nocturia), and sterile urine cultures.〔 Those with interstitial cystitis may have symptoms that overlap with other urinary bladder disorders such as: urinary tract infection (UTI), overactive bladder, urethritis, urethral syndrome, and prostatitis. IC/BPS can result in a quality of life comparable to that of a patient with rheumatoid arthritis, chronic cancer pain, or a patient on kidney dialysis.〔〔(【引用サイトリンク】url=http://www.health.harvard.edu/fhg/updates/update0104d.shtml )〕
==Signs and symptoms==
The most common symptoms of IC/BPS are suprapubic pain, urinary frequency, painful sexual intercourse,〔 and waking up from sleep to urinate.
In general, symptoms may include〔 painful urination described as a burning sensation in the urethra during urination, pelvic pain that is worsened with the consumption of certain foods or drinks, urinary urgency, and pressure in the bladder or pelvis. Other frequently described symptoms are urinary hesitancy (needing to wait for the urinary stream to begin, often caused by pelvic floor dysfunction and tension), and discomfort and difficulty driving, working, or traveling. Pelvic pain experienced by those with IC typically worsens with filling of the urinary bladder and may improve with urination.
During cystoscopy, 5–10% of people with IC are found to have Hunner's ulcers.〔 A person with IC may have discomfort only in the urethra, while another might struggle with pain in the entire pelvis. Interstitial cystitis symptoms usually fall into one of two patterns: significant suprapubic pain with little frequency or a lesser amount of suprapubic pain but with increased urinary frequency.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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